AI Rewrites the Retail Playbook: Real-World Use Cases from Morgan Stanley

📌 Source: This article is based on the podcast episode “AI Rewrites the Retail Playboo…“.

A recent live discussion from the Morgan Stanley Global Consumer & Retail Conference, titled AI Rewrites the Retail Playbook, offers a detailed look at how artificial intelligence is transforming the U.S. retail sector. The episode, hosted by Michelle Weaver and featuring analysts Simeon Guttman and Megan Clap, is based on a comprehensive assessment of AI implementation across consumer and retail companies. The full podcast is available at AI Rewrites the Retail Playbook on Apple Podcasts. The discussion centers on a six-category framework that evaluates AI adoption across breadth, depth, and proprietary initiatives. This structured approach allows for meaningful comparison between companies, helping to identify leaders and early adopters in the AI race.

The framework identifies six core areas of AI application: personalization and refined search, customer acquisition, product innovation, labor productivity, supply chain and logistics, and inventory management. This categorization is not just theoretical. As Simeon Guttman notes, the team analyzed disclosures from covered companies and even used AI to help gather data. The goal was to create an objective benchmark. “We didn’t have a framework until we had the entire universe of all of these AI use cases,” Guttman said. “Once we did, then we were able to compartmentalize them.”

Walmart emerged as a standout example of full-scale AI integration. The company has implemented AI across all six categories. Its Sparky shopping assistant uses generative AI to guide customers through in-store and online experiences. Walmart also partnered with OpenAI to enable ChatGPT-powered search and checkout, a move designed to improve user experience and drive sales. The results are measurable: Walmart reported a 25 percent increase in average shopper spend following the rollout of these tools. This level of integration extends to augmented reality for holiday shopping, computer vision for shelf monitoring, and large language models (LLMs) for inventory replenishment. These applications demonstrate how AI is no longer a side project but a core operational function.

Personalization and refined search are among the most visible and impactful uses of AI in retail. As highlighted in the Morgan Stanley podcast, companies are using AI to streamline product cataloging—automating the process of tagging items with correct descriptions, images, and metadata. This reduces manual labor and accelerates time to market. According to the discussion, this shift is enabling a “step change in personalization.” The goal is not just to show customers items they might like, but to deliver real-time, context-aware recommendations based on behavior and purchase history. This is supported by research from Slite, which notes that personalized search systems can boost productivity by delivering tailored results based on user roles and behavior. The result is a more efficient and satisfying customer journey.

On the supply chain and logistics front, companies like General Mills are using digital twins to improve forecast accuracy. These virtual models of physical operations help simulate different scenarios and optimize performance. General Mills reported a structural improvement in historical productivity savings, increasing from 4 percent annually to 5 percent. This level of quantifiable impact shows that AI is not just about innovation but also about measurable cost reduction. As Megan Clap observed, cost-focused applications like supply chain optimization are often easier to measure than top-line growth initiatives, but they still contribute significantly to long-term competitiveness.

Product innovation is another area where AI is making inroads. Hershey uses algorithms to reallocate advertising spend by zip code based on real-time sell-through data. This allows for more targeted and efficient marketing. The company can adjust campaigns in near real time, maximizing return on ad spend. This use case illustrates how AI enables a shift from broad, static campaigns to dynamic, data-driven strategies. The same principle applies to new product development. AI can analyze consumer trends, social media sentiment, and sales data to identify emerging preferences faster. This reduces time to shelf and increases the likelihood of commercial success.

Labor productivity is a critical driver of AI adoption, particularly in large organizations. The podcast notes that many companies are using AI to automate routine tasks, reduce errors, and improve workflow efficiency. For example, AI-powered tools can assist in scheduling, task assignment, and performance monitoring. This allows human workers to focus on higher-value activities. The Virginia Tech working group report, while focused on education, offers a parallel insight: responsible AI adoption requires not just technology but also training and policy. Their framework includes comprehensive training and professional development, underscoring that technical deployment must be paired with human readiness.

Inventory management is another key area. Walmart’s use of LLMs for inventory replenishment demonstrates how AI can prevent stockouts and overstocking. By analyzing sales patterns, seasonality, and external factors like weather, AI models can predict demand more accurately than traditional methods. This leads to better in-stock rates and reduced waste. The same principle applies to food retailers, where spoilage is a major cost driver. AI can help optimize ordering and distribution, ensuring products reach stores at the right time and in the right quantities.

The discussion also touched on the maturity of AI adoption across different sectors. Megan Clap described food and staples companies as being in the “early innings” of adoption. Most are still building data infrastructure and piloting use cases. However, they have a significant advantage: access to high-frequency consumption data. The challenge lies in moving quickly from pilot to production scale. As Clap noted, “Can these large organizations move with speed and translate that data into action?” This highlights a key tension in enterprise AI: the need for both scale and agility.

The framework used in the Morgan Stanley podcast aligns with broader industry trends. A report from Codewave outlines a similar structure for evaluating AI implementation, emphasizing culture, technology, and design. Their framework includes organizational redesign and future-of-work considerations, which mirror the Virginia Tech report on responsible AI. These external sources reinforce the idea that successful AI integration is not purely technical. It requires changes in how teams work, how leadership thinks about risk, and how institutions govern AI use.

Another critical point from the podcast is the role of partnerships. Walmart’s collaboration with OpenAI is a clear example of how companies are leveraging external expertise. This is not limited to tech giants. Smaller, more agile firms may have an edge in speed and flexibility, even if they lack the scale of giants like Walmart. As Clap noted, both large, well-capitalized companies and nimble startups have a path to success. The key is execution, not just investment.

The podcast also addressed the challenge of bias and transparency in AI systems. While not explicitly discussed in detail, the framework’s emphasis on proprietary initiatives and depth of deployment suggests a focus on quality and accountability. The Virginia Tech report provides context here, advocating for governance structures and policy reviews to ensure responsible use. This is especially important in consumer-facing applications, where biased recommendations or opaque decision-making can erode trust.

Looking ahead, the analysts expect AI adoption to accelerate into 2026. Many companies are planning to scale proven pilots into full operations. The focus will shift from experimentation to impact. As the podcast notes, “It sounds like it’s something to look forward to.” This suggests a transition from proof-of-concept to measurable business outcomes.

The insights from the Morgan Stanley podcast are not limited to corporate strategy. They reflect a broader transformation in how retail works. From search to supply chain, from marketing to labor, AI is redefining every function. The framework they developed offers a practical way to assess progress. It moves beyond hype to a structured, evidence-based approach.

For readers interested in a deeper dive, the full episode remains available on Apple Podcasts. Listening to the original discussion provides context and nuance that a summary cannot capture. The speakers’ emphasis on objectivity, measurement, and real-world impact sets a standard for how AI in retail should be evaluated. This is not a story about futuristic speculation. It’s about what companies are doing today to stay competitive.

The podcast’s framework is a useful tool for investors, executives, and analysts. It provides a clear lens for understanding which companies are truly leading in AI, not just talking about it. By focusing on six core areas and evaluating breadth, depth, and proprietary initiatives, it offers a balanced and actionable assessment. This is exactly the kind of analysis needed in a rapidly evolving market.

As AI continues to reshape retail, the companies that will succeed are those that integrate it deeply, measure its impact, and do so responsibly. The Morgan Stanley discussion provides a roadmap for how to think about this transformation. It is not about replacing humans with machines. It’s about empowering people with better tools and data to make smarter decisions. The path forward is not just technological—it’s organizational, ethical, and strategic.


🎙️ Listen to the Original Podcast

“AI Rewrites the Retail Playboo…”

🍎 Apple Podcasts • 💚 Spotify

This article was written based on the above podcast episode. Give it a listen for the full discussion!